Am. J. Respir. Cell Mol. Biol.,
Volume 18, Number 1, January, 1998 84-90
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stimulated IL-8 mRNA expression and protein release in a time- and dose-dependent
manner, whereas IFN-
alone had no effect. Both cytokines together did not induce greater IL-8 release
compared to TNF-
was more potent in inducing IL-8 release and, together with TNF- |
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  G. Martin, R. J. O'Connell, A. Z. Pietrzykowski, S. N. Treistman, M. F. Ethier, and J. M. Madison Interleukin-4 activates large-conductance, calcium-activated potassium (BKCa) channels in human airway smooth muscle cells Exp Physiol, July 1, 2008; 93(7): 908 - 918. [Abstract] [Full Text] [PDF]
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 K. F. Chung and I. M. Adcock Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction Eur. Respir. J., June 1, 2008; 31(6): 1334 - 1356. [Abstract] [Full Text] [PDF]
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S. Siddiqui, F. Hollins, S. Saha, and C. E. Brightling Inflammatory cell microlocalisation and airway dysfunction: cause and effect? Eur. Respir. J., December 1, 2007; 30(6): 1043 - 1056. [Abstract] [Full Text] [PDF]
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 R. Issa, S. Xie, N. Khorasani, M. Sukkar, I. M. Adcock, K.-Y. Lee, and K. F. Chung Corticosteroid Inhibition of Growth-Related Oncogene Protein-{alpha} via Mitogen-Activated Kinase Phosphatase-1 in Airway Smooth Muscle Cells J. Immunol., June 1, 2007; 178(11): 7366 - 7375. [Abstract] [Full Text] [PDF]
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 A. Berndt, F. J. Derksen, P. J. Venta, S. Ewart, V. Yuzbasiyan-Gurkan, and N. E. Robinson Elevated amount of Toll-like receptor 4 mRNA in bronchial epithelial cells is associated with airway inflammation in horses with recurrent airway obstruction Am J Physiol Lung Cell Mol Physiol, April 1, 2007; 292(4): L936 - L943. [Abstract] [Full Text] [PDF]
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A. J. Ammit, L. M. Moir, B. G. Oliver, J. M. Hughes, H. Alkhouri, Q. Ge, J. K. Burgess, J. L. Black, and M. Roth Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle Am J Physiol Lung Cell Mol Physiol, January 1, 2007; 292(1): L199 - L206. [Abstract] [Full Text] [PDF]
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 V. Govindaraju, M.-C. Michoud, M. Al-Chalabi, P. Ferraro, W. S. Powell, and J. G. Martin Interleukin-8: novel roles in human airway smooth muscle cell contraction and migration Am J Physiol Cell Physiol, November 1, 2006; 291(5): C957 - C965. [Abstract] [Full Text] [PDF]
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S. Nozell, T. Laver, K. Patel, and E. N. Benveniste Mechanism of IFN-beta-Mediated Inhibition of IL-8 Gene Expression in Astroglioma Cells J. Immunol., July 15, 2006; 177(2): 822 - 830. [Abstract] [Full Text] [PDF]
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R. Issa, S. Xie, K.-Y. Lee, R. D. Stanbridge, P. Bhavsar, M. B. Sukkar, and K. F. Chung GRO-{alpha} regulation in airway smooth muscle by IL-1beta and TNF-{alpha}: role of NF-{kappa}B and MAP kinases Am J Physiol Lung Cell Mol Physiol, July 1, 2006; 291(1): L66 - L74. [Abstract] [Full Text] [PDF]
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 J. Kanefsky, M. Lenburg, and C.-M. Hai Cholinergic Receptor and Cyclic Stretch-Mediated Inflammatory Gene Expression in Intact ASM Am. J. Respir. Cell Mol. Biol., April 1, 2006; 34(4): 417 - 425. [Abstract] [Full Text] [PDF]
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Y. Chiba, M. Murata, H. Ushikubo, Y. Yoshikawa, A. Saitoh, H. Sakai, J. Kamei, and M. Misawa Effect of Cigarette Smoke Exposure In Vivo on Bronchial Smooth Muscle Contractility In Vitro in Rats Am. J. Respir. Cell Mol. Biol., December 1, 2005; 33(6): 574 - 581. [Abstract] [Full Text] [PDF]
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 K. F. Chung The Role of Airway Smooth Muscle in the Pathogenesis of Airway Wall Remodeling in Chronic Obstructive Pulmonary Disease Proceedings of the ATS, November 1, 2005; 2(4): 347 - 354. [Abstract] [Full Text] [PDF]
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 M. A. Birrell, E. Hardaker, S. Wong, K. McCluskie, M. Catley, J. De Alba, R. Newton, S. Haj-Yahia, K. T. Pun, C. J. Watts, et al. I{kappa}-B Kinase-2 Inhibitor Blocks Inflammation in Human Airway Smooth Muscle and a Rat Model of Asthma Am. J. Respir. Crit. Care Med., October 15, 2005; 172(8): 962 - 971. [Abstract] [Full Text] [PDF]
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G. E. Morris, M. K. B. Whyte, G. F. Martin, P. J. Jose, S. K. Dower, and I. Sabroe Agonists of Toll-like Receptors 2 and 4 Activate Airway Smooth Muscle via Mononuclear Leukocytes Am. J. Respir. Crit. Care Med., April 15, 2005; 171(8): 814 - 822. [Abstract] [Full Text] [PDF]
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E. F. M. Wouters Local and Systemic Inflammation in Chronic Obstructive Pulmonary Disease Proceedings of the ATS, April 1, 2005; 2(1): 26 - 33. [Abstract] [Full Text] [PDF]
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 M. F. Ethier, E. Cappelluti, and J. M. Madison Mechanisms of Interleukin-4 Effects on Calcium Signaling in Airway Smooth Muscle Cells J. Pharmacol. Exp. Ther., April 1, 2005; 313(1): 127 - 133. [Abstract] [Full Text] [PDF]
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S. Xie, M. B. Sukkar, R. Issa, U. Oltmanns, A. G. Nicholson, and K. F. Chung Regulation of TGF-{beta}1-induced connective tissue growth factor expression in airway smooth muscle cells Am J Physiol Lung Cell Mol Physiol, January 1, 2005; 288(1): L68 - L76. [Abstract] [Full Text] [PDF]
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M. B. Sukkar, R. Issa, S. Xie, U. Oltmanns, R. Newton, and K. F. Chung Fractalkine/CX3CL1 production by human airway smooth muscle cells: induction by IFN-{gamma} and TNF-{alpha} and regulation by TGF-{beta} and corticosteroids Am J Physiol Lung Cell Mol Physiol, December 1, 2004; 287(6): L1230 - L1240. [Abstract] [Full Text] [PDF]
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R. A. Panettieri Jr. Effects of Corticosteroids on Structural Cells in Asthma and Chronic Obstructive Pulmonary Disease Proceedings of the ATS, November 1, 2004; 1(3): 231 - 234. [Abstract] [Full Text] [PDF]
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 C E Brightling and I D Pavord Location, location, location: microlocalisation of inflammatory cells and airway dysfunction Thorax, September 1, 2004; 59(9): 734 - 735. [Full Text] [PDF]
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I. Nomura, E. Goleva, M. D. Howell, Q. A. Hamid, P. Y. Ong, C. F. Hall, M. A. Darst, B. Gao, M. Boguniewicz, J. B. Travers, et al. Cytokine Milieu of Atopic Dermatitis, as Compared to Psoriasis, Skin Prevents Induction of Innate Immune Response Genes J. Immunol., September 15, 2003; 171(6): 3262 - 3269. [Abstract] [Full Text] [PDF]
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 V. Brusasco and R. Pellegrino Invited Review: Complexity of factors modulating airway narrowing in vivo: relevance to assessment of airway hyperresponsiveness J Appl Physiol, September 1, 2003; 95(3): 1305 - 1313. [Abstract] [Full Text] [PDF]
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Y. Amrani, O. Tliba, D. Choubey, C.-D. Huang, V. P. Krymskaya, A. Eszterhas, A. L. Lazaar, and R. A. Panettieri Jr. IFN-gamma inhibits human airway smooth muscle cell proliferation by modulating the E2F-1/Rb pathway Am J Physiol Lung Cell Mol Physiol, June 1, 2003; 284(6): L1063 - L1071. [Abstract] [Full Text] [PDF]
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S. Baraldo, D. S. Faffe, P. E. Moore, T. Whitehead, M. McKenna, E. S. Silverman, R. A. Panettieri Jr., and S. A. Shore Interleukin-9 influences chemokine release in airway smooth muscle: role of ERK Am J Physiol Lung Cell Mol Physiol, June 1, 2003; 284(6): L1093 - L1102. [Abstract] [Full Text] [PDF]
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C.-D. Huang, O. Tliba, R. A. Panettieri Jr., and Y. Amrani Bradykinin Induces Interleukin-6 Production in Human Airway Smooth Muscle Cells: Modulation by Th2 Cytokines and Dexamethasone Am. J. Respir. Cell Mol. Biol., March 1, 2003; 28(3): 330 - 338. [Abstract] [Full Text] [PDF]
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H. J. Patel, M. G. Belvisi, D. Bishop-Bailey, M. H. Yacoub, and J. A. Mitchell Activation of Peroxisome Proliferator-Activated Receptors in Human Airway Smooth Muscle Cells Has a Superior Anti-inflammatory Profile to Corticosteroids: Relevance for Chronic Obstructive Pulmonary Disease Therapy J. Immunol., March 1, 2003; 170(5): 2663 - 2669. [Abstract] [Full Text] [PDF]
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S. V. Culpitt, D. F. Rogers, P. Shah, C. De Matos, R. E. K. Russell, L. E. Donnelly, and P. J. Barnes Impaired Inhibition by Dexamethasone of Cytokine Release by Alveolar Macrophages from Patients with Chronic Obstructive Pulmonary Disease Am. J. Respir. Crit. Care Med., January 1, 2003; 167(1): 24 - 31. [Abstract] [Full Text] [PDF]
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 W. T. Gerthoffer and C. A. Singer Secretory Functions of Smooth Muscle: Cytokines and Growth Factors Mol. Interv., November 1, 2002; 2(7): 447 - 456. [Abstract] [Full Text] [PDF]
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S. J. Hirst, M. P. Hallsworth, Q. Peng, and T. H. Lee Selective Induction of Eotaxin Release by Interleukin-13 or Interleukin-4 in Human Airway Smooth Muscle Cells Is Synergistic with Interleukin-1beta and Is Mediated by the Interleukin-4 Receptor alpha -Chain Am. J. Respir. Crit. Care Med., April 15, 2002; 165(8): 1161 - 1171. [Abstract] [Full Text] [PDF]
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 A. E. Varner The Increase in Allergic Respiratory Diseases : Survival of the Fittest? Chest, April 1, 2002; 121(4): 1308 - 1316. [Abstract] [Full Text] [PDF]
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G. W. Chalmers, K. J. MacLeod, L. Thomson, S. A. Little, C. McSharry, and N. C. Thomson Smoking and Airway Inflammation in Patients With Mild Asthma Chest, December 1, 2001; 120(6): 1917 - 1922. [Abstract] [Full Text] [PDF]
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Y. AMRANI, P. E. MOORE, R. HOFFMAN, S. A. SHORE, and R. A. PANETTIERI JR. Interferon-gamma Modulates Cysteinyl Leukotriene Receptor-1 Expression and Function in Human Airway Myocytes Am. J. Respir. Crit. Care Med., December 1, 2001; 164(11): 2098 - 2101. [Abstract] [Full Text] [PDF]
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S. Page, A. J. Ammit, J. L. Black, and C. L. Armour Human mast cell and airway smooth muscle cell interactions: implications for asthma Am J Physiol Lung Cell Mol Physiol, December 1, 2001; 281(6): L1313 - L1323. [Abstract] [Full Text] [PDF]
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M. P. HALLSWORTH, L. M. MOIR, D. LAI, and S. J. HIRST Inhibitors of Mitogen-activated Protein Kinases Differentially Regulate Eosinophil-activating Cytokine Release from Human Airway Smooth Muscle Am. J. Respir. Crit. Care Med., August 15, 2001; 164(4): 688 - 697. [Abstract] [Full Text] [PDF]
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J. M. Madison and M. F. Ethier Interleukin-4 Rapidly Inhibits Calcium Transients in Response to Carbachol in Bovine Airway Smooth Muscle Cells Am. J. Respir. Cell Mol. Biol., August 1, 2001; 25(2): 239 - 244. [Abstract] [Full Text] [PDF]
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J. C. LAPORTE, P. E. MOORE, S. BARALDO, M.-H. JOUVIN, T. L. CHURCH, I. N. SCHWARTZMAN, R. A. PANETTIERI Jr, J.-P. KINET, S. A. SHORE, and S. A. SHORE Direct Effects of Interleukin-13 on Signaling Pathways for Physiological Responses in Cultured Human Airway Smooth Muscle Cells Am. J. Respir. Crit. Care Med., July 1, 2001; 164(1): 141 - 148. [Abstract] [Full Text] [PDF]
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P. G. Gibson, J. L. Simpson, and N. Saltos Heterogeneity of Airway Inflammation in Persistent Asthma : Evidence of Neutrophilic Inflammation and Increased Sputum Interleukin-8 Chest, May 1, 2001; 119(5): 1329 - 1336. [Abstract] [Full Text] [PDF]
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N. Lazzeri, M. G. Belvisi, H. J. Patel, M. H. Yacoub, K. Fan Chung, and J. A. Mitchell Effects of Prostaglandin E2 and cAMP Elevating Drugs on GM-CSF Release by Cultured Human Airway Smooth Muscle Cells . Relevance to Asthma Therapy Am. J. Respir. Cell Mol. Biol., January 1, 2001; 24(1): 44 - 48. [Abstract] [Full Text]
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 L. PANG and A. J. KNOX Regulation of TNF-{alpha}-induced eotaxin release from cultured human airway smooth muscle cells by {beta}2-agonists and corticosteroids FASEB J, January 1, 2001; 15(1): 261 - 269. [Abstract] [Full Text] [PDF]
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 L. H. Thomas, M. I. Y. Wickremasinghe, M. Sharland, and J. S. Friedland Synergistic Upregulation of Interleukin-8 Secretion from Pulmonary Epithelial Cells by Direct and Monocyte-Dependent Effects of Respiratory Syncytial Virus Infection J. Virol., September 15, 2000; 74(18): 8425 - 8433. [Abstract] [Full Text]
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L. Pang and A. J. Knox Synergistic Inhibition by beta 2-Agonists and Corticosteroids on Tumor Necrosis Factor-alpha -Induced Interleukin-8 Release from Cultured Human Airway Smooth-Muscle Cells Am. J. Respir. Cell Mol. Biol., July 1, 2000; 23(1): 79 - 85. [Abstract] [Full Text]
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J. C. Hedges, C. A. Singer, and W. T. Gerthoffer Mitogen-Activated Protein Kinases Regulate Cytokine Gene Expression in Human Airway Myocytes Am. J. Respir. Cell Mol. Biol., July 1, 2000; 23(1): 86 - 94. [Abstract] [Full Text]
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S. McKay, S. J. Hirst, M. B.-d. Haas, J. C. de Jongste, H. C. Hoogsteden, P. R. Saxena, and H. S. Sharma Tumor Necrosis Factor-alpha Enhances mRNA Expression and Secretion of Interleukin-6 in Cultured Human Airway Smooth Muscle Cells Am. J. Respir. Cell Mol. Biol., July 1, 2000; 23(1): 103 - 111. [Abstract] [Full Text]
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M. R. van Scott, J. P. Justice, J. F. Bradfield, E. Enright, A. Sigounas, and S. Sur IL-10 reduces Th2 cytokine production and eosinophilia but augments airway reactivity in allergic mice Am J Physiol Lung Cell Mol Physiol, April 1, 2000; 278(4): L667 - L674. [Abstract] [Full Text] [PDF]
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S. MARUOKA, S. HASHIMOTO, Y. GON, I. TAKESHITA, and T. HORIE PAF-induced RANTES Production by Human Airway Smooth Muscle Cells Requires Both p38 MAP Kinase and Erk Am. J. Respir. Crit. Care Med., March 1, 2000; 161(3): 922 - 929. [Abstract] [Full Text] [PDF]
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J. L. Pype, L. J. Dupont, P. Menten, E. Van Coillie, G. Opdenakker, J. Van Damme, K. Fan Chung, M. G. Demedts, and G. M. Verleden Expression of Monocyte Chemotactic Protein (MCP)-1, MCP-2, and MCP-3 by Human Airway Smooth-Muscle Cells . Modulation by Corticosteroids and T-Helper 2 Cytokines Am. J. Respir. Cell Mol. Biol., October 1, 1999; 21(4): 528 - 536. [Abstract] [Full Text]
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N. Hagimoto, K. Kuwano, M. Kawasaki, M. Yoshimi, Y. Kaneko, R. Kunitake, T. Maeyama, T. Tanaka, and N. Hara Induction of Interleukin-8 Secretion and Apoptosis in Bronchiolar Epithelial Cells by Fas Ligation Am. J. Respir. Cell Mol. Biol., September 1, 1999; 21(3): 436 - 445. [Abstract] [Full Text]
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K F Chung and P J Barnes Cytokines in asthma Thorax, September 1, 1999; 54(9): 825 - 857. [Full Text]
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Y. Amrani, A. L. Lazaar, and R. A. Panettieri Jr. Up-Regulation of ICAM-1 by Cytokines in Human Tracheal Smooth Muscle Cells Involves an NF-{kappa}B-Dependent Signaling Pathway That Is Only Partially Sensitive to Dexamethasone J. Immunol., August 15, 1999; 163(4): 2128 - 2134. [Abstract] [Full Text] [PDF]
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P. J. Patel, D. E. Faunce, M. S. Gregory, L. A. Duffner, and E. J. Kovacs Elevation in Pulmonary Neutrophils and Prolonged Production of Pulmonary Macrophage Inflammatory Protein-2 after Burn Injury with Prior Alcohol Exposure Am. J. Respir. Cell Mol. Biol., June 1, 1999; 20(6): 1229 - 1237. [Abstract] [Full Text]
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O. GHAFFAR, Q. HAMID, P. M. RENZI, Z. ALLAKHVERDI, S. MOLET, J. C. HOGG, S. A. SHORE, A. D. LUSTER, and B. LAMKHIOUED Constitutive and Cytokine-Stimulated Expression of Eotaxin by Human Airway Smooth Muscle Cells Am. J. Respir. Crit. Care Med., June 1, 1999; 159(6): 1933 - 1942. [Abstract] [Full Text]
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M. L. Watson, A.-M. White, E. M. Campbell, A. W. Smith, J. Uddin, T. Yoshimura, and J. Westwick Anti-Inflammatory Actions of Interleukin-13 . Suppression of Tumor Necrosis Factor-alpha and Antigen-Induced Leukocyte Accumulation in the Guinea Pig Lung Am. J. Respir. Cell Mol. Biol., May 1, 1999; 20(5): 1007 - 1012. [Abstract] [Full Text]
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M. P. Hallsworth, C. P. C. Soh, C. H. C. Twort, T. H. Lee, and S. J. Hirst Cultured human airway smooth muscle cells stimulated by interleukin-1beta enhance eosinophil survival. Am. J. Respir. Cell Mol. Biol., December 1, 1998; 19(6): 910 - 919. [Abstract] [Full Text]
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 P. J. Barnes, K. F. Chung, and C. P. Page Inflammatory Mediators of Asthma: An Update Pharmacol. Rev., December 1, 1998; 50(4): 515 - 596. [Abstract] [Full Text] [PDF]
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P. J. BARNES Pharmacology of Airway Smooth Muscle Am. J. Respir. Crit. Care Med., November 1, 1998; 158(2007): S123 - S132. [Abstract] [Full Text] [PDF]
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S. J. HIRST and T. H. LEE Airway Smooth Muscle as a Target of Glucocorticoid Action in the Treatment of Asthma Am. J. Respir. Crit. Care Med., November 1, 1998; 158(2007): S201 - S206. [Abstract] [Full Text] [PDF]
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I. Rahman and W. MacNee Role of transcription factors in inflammatory lung diseases Thorax, July 1, 1998; 53(7): 601 - 612. [Full Text]
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