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Figure 5.
SMA expression in normal lung and in early-stage hyperoxic PH. In the normal lung,
SMA is expressed by the smooth-muscle cells of bronchioli (A and B) and terminal bronchioli (C, tb) and in associated vessels (B, tw = TWOMA, see ANALYSIS OF LUNG
VESSEL POPULATIONS in RESULTS; C, tbv = terminal bronchiolar vessel); expression is low or absent in alveolar vessels of normal lung (D,
alveolar wall vessel at double arrow and alveolar wall vessel, ED 29 µm at single arrow) and in the hyperoxic lung at Day 4 (E, alveolar
wall vessel, ED 45 µm). Bars = 50 µm.