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Figure 6.
SMA expression in alveolar vessels in late-stage hyperoxic PH. In the hyperoxic lung at Day 28, as in normal lung,
SMA is
expressed by airway smooth-muscle cells and in associated vessels (A, bv = bronchial vessel; B, tw = TWOMA, ED 138 µm; C, tbv = terminal bronchiolar vessel, ED 50 µm). In contrast to normal lung, many alveolar vessels are thick-walled and have
SMA-positive
cells (D, muscular alveolar vessel, ED 26.4 µm; E, muscular alveolar duct vessel, ED 32 µm; F, partially muscular alveolar wall vessel,
ED 33 µm). Bars = 25 µm.