Published ahead of print on November 10, 2006, doi:10.1165/rcmb.2006-0090OC Am. J. Respir. Cell Mol. Biol., Volume 36, Number 4, April 2007, 491-496 A more recent version of this article appeared on April 1, 2007
Submitted on February 28, 2006 Functional Polymorphism in the Suppressor of Cytokine Signaling 1 Gene Associated With Adult AsthmaMichishige Harada1,1 Laboratory for Genetics of Allergic Diseases, The Institute of Physical and Chemical Research (RIKEN), SNP Research Center, Kanagawa, Japan, 2 Laboratory for Genetics of Allergic Diseases, The Institute of Physical and Chemical Research (RIKEN), SNP Research Center, Kanagawa, Japan; Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Public Health, Kyoto, Japan, 3 Laboratory for Genetics of Allergic Diseases, The Institute of Physical and Chemical Research (RIKEN), SNP Research Center, Kanagawa, Japan; Department of Microbiology and Immunology, Kagoshima University Dental School, Kagoshima, Japan, 4 Department of Pediatric Allergy, Osaka Prefectural Medical Center for Respiratory and Allergic Diseases, Habikino Osaka, Japan, 5 School of Human Nursing, The University of Shiga Prefecture, Shiga, Japan, 6 Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Public Health, Kyoto, Japan, 7 Department of Otolaryngology, Japanese Red Cross Society, Wakayama Medical Center, Wakayama, Japan, 8 Department of Otorhinolaryngology, Jikei University School of Medicine, Minato-ku Tokyo, Japan, 9 Department of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, Japan, 10 Department of Public Health, Chiba University, Graduate School of Medicine, Chiba, Japan, 11 Laboratory of Molecular Medicine, The University of Tokyo, The Institute of Medical Science, Tokyo, Japan * To whom correspondence should be addressed. E-mail: tamari{at}src.riken.jp.
Suppressor of cytokine signaling (SOCS) 1 is an essential physiological regulator of the interferon (IFN)-
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