Cover: TE mRNA expression during pulmonary development. In situ hybridizations were used to detect TE mRNA in lung sections from embryonic Day 16 (a); fetal Days 18 (b) and 20 (c); and ppd 1 (d), 7 (e), and 30 ( f ) animals. Short arrows denote PA, long arrows denote airways, and the open arrow (a) denotes the aorta in a to f. TE mRNA was first detected in the aorta and pulmonary vessels during embryonic life, and later in pulmonary airway cells during fetal life. Although TE mRNA remained detectable in vascular tissue at basal levels throughout adult life, its expression was undetectable in airway cells of the adult animal. For further information, see the article by Belknap and colleagues 24.
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