Cover: Lung sections from 23-day-old Fischer F-344 rats killed 5 d after the intranasal inoculation of virus-free medium (left) or 40 µl of a suspension containing 5 × 10⁴ TCID₅₀/0.1 ml of RSV (right). Immunoperoxidase staining was performed using a pool of mouse mABs composed of four clones specific for the proteins M2, P, F, and N of human RSV. The brown reaction reveals the presence of viral antigens on the membranes and in the cytoplasm of bronchiolar epithelial cells from the RSV-inoculated rats. There was no detectable virus in the lungs of control rats inoculated with virus-free medium. Internal scale = 50 µm. For more information see article by King and colleagues 101.
[Table of Contents]