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Mucin is secreted from airway epithelial cells in a ligand-regulated manner. In mice 3 days after antigen exposure, increasing concentrations of aerosolized ATP (0.1-100 mM, 5 min) caused a dose-dependent decrease in AB-PAS and PAFS staining. For more information see article by Evans and colleagues beginning on page 382.
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Proc. Am. Thorac. Soc. Am. J. Respir. Crit. Care Med.
Copyright © 2007 American Thoracic Society.